When a female has a hormone imbalance in their endocrine system, they can develop symptoms that range from subtle to debilitating. This means that there is either too much or too little of a woman’s hormones being produced somewhere within the endocrine system. Symptoms of a hormonal imbalance in women include heavy, irregular, or uncomfortable periods, decreased bone density, hot flashes and night sweats, vaginal dryness, breast tenderness, indigestion, and constipation or diarrhea.